Endocrine Abstracts

Introduction: Central diabetes insipidus (CDI) occurs due to deficient secretion of arginine vasopressin (AVP) or antidiuretic hormone (ADH) by the posterior pituitary. It is a rare disease with an estimated prevalence of 1:25000. CDI can be acquired or congenital, secondary to malformation or genetics. Familial CDI (genetic inheritance) is mainly autosomal dominant. More than 80 mutations in the AVP gene have been described. In hereditary CDI, the age of onset is variable. Sy...